CBDV vs. CBD: The Minor Cannabinoid with Major Neuro-Potential

THC, CBD and a whole host of other compounds found in marijuana

THC, CBD and a whole host of other compounds found in marijuana meant that cannabis has much more to offer than a brain stimulating hallucination. With hundreds of cannabinoids within the hemp plant already known to science, it’s only a matter of time before delapp to the enhancement of marijuana to limbcon resonates within the field. Enter Cannabidivarin or simply CBDV, a rather interesting cannabis component. It is synonymous with CBD, both being variants of the same plant which has captivated scientists and fans of health living in recent times. With the envisaged advantages of CBD already complementing wellness goals for most individuals, the demand for such minor cannabinoids is increasing. CBDV on the other hand, is a novel niche. It’s not about whether one works better than the other, it’s about appreciating how each can be utilized in treating different conditions. This document is everything written on these two non-psychoactive chemicals – starting with their chemical compositions and the current advances in the respective research, highlighting the peculiar promise of the CBDV.

An Introduction to CBD. A Refresher!

Let’s talk about the CBDV vs CBD. However, shall we make things complicated without clarifying what CBD means? No! We don’t want that. Why do I say cannabis without thinking? I mean why do I say cannabis and right after ‘the second most important chemical present’ follows? Why did it follow? To an average person, CBD will be hemp, which speaks about how she spends her days. This is because unlike THC, unlike intoxication inducing marijuana, I am happy to a lesser extent to say ‘extraction done from hemp’ rather than ‘hashish’. So let me tell you what it does.

There are tens of thousands of Americans who use CBD and they do so for many different peripheral reasons, which have been endorsed by a host of scholarly propounded works. Its premature momentous effects are to be more heavily associated with anxiety management, easing pain and inflammation, and enhancing sleep. It is their lawful status of consumption at least as allowed by 2018 Farm Bill and its oversized supply that explains why over the counter medicines are commonly off limits oriented CBD products. The respect CBD enjoys is due to the stimulation it expands on numerous processes in the organism: endocannabinoid system or in layman terms, a system of regulation formed by normal cells present in the body.

Introducing: The other Cannabinoid, that is, CBDV. And its Expectations.

When we say that Cannabidivarin, or simply CBDV, is a CBD homolog, what do we actually mean? This means that molecular structures of these two are almost identical except for a single replacement that the other lacks. With respect to the psychoactive profile, however, both CBD and CBDV do not exhibit any such characteristic in their effects. In terms of content, it is classified as a tracer component because it does not tend to be found in high proportions relative to CBD or THC.

One peculiar pattern though, CBDV is common in large percentages in especially African and Central Asian landrace indica varieties. But due to improvement in techniques of farming and breeding, there are now marijuana feminized strains that are high in CBDV so it can be more easily attainable. The conclusion of the CBDV vs CBD debate revolves around the uniquely potent benefits the CBDV cannabinoid seems to have, as shown by early studies, especially in relation to the nervous system.

CBDV Vs CBD: Highlights Of The Most Essential Issues

To understand the comparison between CBDV vs CBD, it is useful that each of the discussed compounds are placed together in one text. Several factors which could affect the application of these compounds are also useful in making such comparisons.

Attribute CBDV (Cannabidivarin) CBD (Cannabidiol)
Structure This has a propyl (3 carbon) side chain. This has a pentyl (5 carbon) side chain.
Main Emphasis in Research Issues with the nervous system (such as autism and seizures), ejection of anxieties, non-specific nerve ailments. Used to manage anxiety, tempering of inflammation, pain release, sedating that promotes sleep, achieving improved health.
Components of Activity Enhances TRP channels, dampens down TRPV1 channels. Modulates the endocannabinoids as well as the serotonin receptors to a greater extent.
Presence in Markets Uncommon, occurs in specialty full-spectrum oils and in isolate form. Generally marketed as isolates, or with broad spectrum and full spectrum concentration.

Let’s Break It Down: Molecules Matter

The main physical distinction between CBDV versus CBD is in their structural composition. These two compounds have almost the same structure, but differ in the number of carbons attached to the phenol ring. In CBD vs CBDV there is a difference wherein CBD is pentyl conductivity alcohol whereas CBDV is propyl alcohol. May appear somewhat irrelevant, nonetheless in the biochemical world all things are dimensional. In other words, consider two identical keys, however, if one key has a slightly shorter end, then the key will function in a lock filled with pins differently. Similarly, the slight structural difference alters the CBDV and CBD’s ability to interact or bind to various receptors and channels present in the body. That is why their differences although overlapping at times, also possess quite differently. This is some perspective on why the discussion of CBDV vs CBD actually starts here at the molecular level.

Exploring at Length the Present Affairs: Merits of CBDV

CBD focused research is already at an advanced stage compared to the stage of research on CBDV, which can be best described as infancy, but the earlier results are very promising. Most researchers are highly optimistic about disorders due to its compound thus can be said to be in favor of the CBDV vs CBD battle.

Neuro Triumph: Impact on Autism Spectrum Disorder (ASD)

CBDV has been studied quite a bit with regards to whether it can assist in alleviating the symptoms of Autism Spectrum Disorder. In preclinical research, studies have been carried out to show how CBDV can improve and restore social and cognitive deficits by enhancing the functioning of the brain. As a matter of fact, in pilot clinical trials, its effects to mitigate the irritability in people suffering from ASD and reduce the number of repetitive behaviors were investigated. These studies have not been completed yet, however, they indicate that the cannabinoid CBDV is promising for disorders that are related to the behavior of individuals affected by such disorders.

Epileptic Episodes

Similar in nature to its relative CBD, which serves as the main component in the only FDA-approved anti-seizure drug for epilepsy – Epidiolex, CBDV seemingly possesses potent anti-epileptic qualities in this sense. In preclinical trials on epilepsy, researchers have been able to demonstrate that the compound can suppress electroencephalographic changes and however it has been more evident in some of the cases. In retrospections, it is hypothesized that the mechanism is realized by TRP channels and their influence on seizure activity. Therefore, the issue of CBDV vs CBD is most important to people who are interested in cannabinoids for the purpose of controlling seizures.

Sickness and Throwing Up

Another potential use of therapeutic interest is using CBDV as an effective anti-emetic. A paper published in 2013 concluded that CBDV has the potential to alleviate nausea in empirical settings. Furthermore, it seems to counteract nausea by engaging the 5HT1A receptors. This might help mitigate nausea caused by chemotherapy or other treatments that are associated with nausea as one of the side effects.

Congenital Muscle Disorder and Rett’s Syndrome

Latest additional assessment CBDV is also investigated in the context of assisting with such rare diseases. Found in experiments to examine its capabilities in improving motor skills and cognitive functions in models of Rett’s syndrome. Also, preliminary evidence suggests that CBDV can reduce inflammation and enhance – to an extent – the muscular tissue regeneration in Duchenne Muscular Dystrophy giving an indication of its extended activity.

Going back to the basics about CBD

In order to understand the CBDV vs CBD it helps to recall the powerful nature of CBD. It has become a legendary compound for a number of reasons, all of which are supported by a significant body of research, and thousands of user experiences that have highlighted its valuable properties.

Worry and Tension

It is probably the most well-known effect of CBD – it is the calming effect. It engages with regions of the brain that have serotonin receptors, and helps to elevate the mood and relax in this way. Most people take it to prevent or work through daily strain, social phobias and other phobic disorders.

Pain and Inflammation

It is a well-known fact that CBD is an effective anti-inflammatory agent. The action takes place through the ECS where the CBD binds to the receptors to decrease inflammation in different parts of the body due to which it is commonly used for the treatment of chronic pain including arthritis and even normal soreness or muscle recovery post exercise.

Sleep Support

Since CBD addresses the very causes of non-restfulness such as infections, anxiety, stress, or pain, it can prove beneficial to quite a lot of individuals in helping them to have a restful night of sleep. Contrary to most perceptions, it doesn’t serve as a ‘sedative’, but balances the body instead, making it easier to sleep and to remain asleep for the required amount of time.

How Do They Work? A Look at the Mechanism of Action

The CBDV vs CBD benefits analysis brings out distinctions based on how they work. Since both compounds do not contain any intoxicating sensations as they don’t bind to the cannabinoid receptor CB1 which is the main target for THC, each of them follows a different pathway to bring about their effects.

It provides useful CBD influence as there is a consideration of the indirect impact on the endocannabinoid system. It acts to block an enzyme that destroys the “happy” anandamide, therefore most of this beneficial endocannabinoid is able to remain active in the body. It is also able to interact with the receptors for serotonin, opioid, and dopamine.

The mechanism of action of CBDV appears to be more focused. Most of its effects are targeted at the Transient Receptor Potential (TRP) channels. These channels facilitate the experience of different senses, icy cold, hot, movements, pain etc. CBDV works instead to reverse the modulation of pain and neuronal hyper-excitability potent in relation to its anti-seizure activity through the desensitization of selective TRP channels such as TRPV1 (capsaicin receptor) channels.

Legislative And Sale Of CBDV – Is this compound considered to be lawful?

Here append your text accordingly according to the labels’ text, for instance, what in terms of CBDV vs CBD. The legal status of CBD with respect to its cannabinoid counterpart, CBDV in the US also commonly depends on the source. The 2018 Farm Bill permitted hemp products including derivatives with Delta 9 THC content of less than 0.3% on the federal level. Therefore, CBDV derived from the sanctioned hemp species is legitimate as it pertains to federal laws. Only that as in other cases there are states with their hemp derivatives cannabinoid regulations, therefore a safe bet would be a reference to the appropriate statutes in one’s abode.

Considering the market saturation, the CBDV vs CBD production diversity disparity is apparent. CBD is omnipresent, it comes in form of tinctures, oral capsules, topicals and even edibles like candies. CBDV on the other hand is quite scarce but readily available in the market. Some such CBD products include it to attain the entourage effect full spectrum. However, some tinctures are specifically manufactured with CBDV as the main/sole cannabinoid, whether as an isolate or in a one-to-one ratio with CBD, do also exist.

Which one to Go for: When to Choose CBD, CBDV or Both?

When you have to make a choice between two different things such as CBDV vs CBD, it is wise to consider the things that your body needs specifically. One cannot give a universal answer to that question, but here is a way in which one can easily choose:

  • Pick CBD where: You are a novice in the use of cannabinoids in health and would like to enhance well-being. It helps alleviate anxiety and stress, headaches, and is even great for people who have trouble sleeping. The basic availability and a large number of studies make it the most appropriate choice for beginners.
  • Pick CBDV where: You wish to test its effects which are more focused on the brain. In the case where the cannabinoids are being applied for the purpose of helping with epilepsy, vomiting, or the effects of ASD (this should ALWAYS be done under the care of a qualified health provider), then CBDV can be regarded as a particular focus to explore.

Think About Both (Full Range): It therefore follows that, there is no need to pick one or the other. The ‘entourage effect’ is a phenomenon well-known among the cannabis research community. According to this school of thought, in the presence of each other, the cannabinoids perform better than any one alone. When choosing a full spectrum product which includes a variety of cannabinoids – for example, Cannabidiol and Cannabidivarin – it is believed that the benefits are maximized.

Common Inquiries And Their Answers (F. A. Q.)

  • Is it possible to get high from CBDV? Absolutely not. Neither CBD nor CBDV are intoxicants for neither contain psychoactive elements. As for the action of ALLI into the system, it does not snug up to any mu receptors or any other receptor systems included, so it does not possess and produce that ‘high’ feeling of THC.
  • What distinguishes CBDV from CBD the most? In the CBDV vs. CBD context, the most significant distinction is the configuration. A short-carbon chain is present in CBDV instead of a long-carbon chain as in CBD, hence it binds and operates on the cells in a different manner. This consequently makes the primary focus of studies for CBDV neurological disorders, while for CBD it is health and wellness in general.
  • Is it possible to take CBD and CBDV concurrently? Yes, it is possible. These compounds often co-exist in nature within the hemp plant and are incorporated into most full spectrum cannabinoid formulations. Combining them can result in a potential additional effect or increased benefits.
  • Can we say that CBDV is more potent than CBD? It would be incorrect to say that one is stronger than the other. They serve different purposes. For example, CBDV might be more useful for targeting epilepsy-related TRP channels than CBD. Whereas, for treating anxiety, CBD would be the choice over CBDV. The CBDV vs CBD query depicts the issue of “which instrument is for which purpose”.

Final Thoughts

There has been a discussion regarding CBDV vs CBD which has brought out the vast potential of the hemp plant. Even though CBD is still the more popular cannabinoid and caters to more general needs such as wellness, pain and anxiety, CBDV unlike CBD promotes a different set of effects on the brain. Apart from this, its anti-seizure, anti-nausea, and anti-ASD
effects make it a perfect candidate as more natural therapeutics become available in the future. As the exploration of lesser-known cannabinoids evolves and appreciates drugs such as CBDV, there will be more options available to the consumer which are tailored to their specific requirements. It is not an ‘either or’, it is a ‘both’ because each one offers certain functions in a cannabis spectrum that contains many more cannabinoids.

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